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Even patients who dont lose weight on GLP-1s will often still see improvements in blood sugar if they have diabetes

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In addition, there are precautions for their use in people with pancreatitis and diabetic retinopathy, the incidence of which is generally increased in T2DM

The study also found that adults taking a GLP-1 had an increased risk for interstitial nephritis, a type of kidney condition that Al-Aly says is almost like an allergic reaction that the kidney mounts against certain drugs. He says more long-term studies are needed to better understand the risks and benefits of prolonged use