FIGURE 1 2 Literature search strategy To support the narrative synthesis, a focused literature search was conducted across PubMed, Web of Science, ScienceDirect, and SpringerLink, targeting English-language, peer-reviewed articles published between 2010 and 2025
Besides, 75% of PKU patients are compound heterozygotes, resulting in interallelic complementation of the mutated tetrameric PAH enzyme [19, 27]
Treatment tailored to condition urgency/severity
Interestingly, no associations were observed for GSH changes in buccal cells
The maximum tumour mean diameter permitted was 15 mm with no single diameter greater than 18 mm
Almost all are administered subcutaneously, although oral semaglutide is currently available in Spain (see below)