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Specific pathways affected include TGF-beta superfamily signaling, Wnt signaling, antioxidant defense (including superoxide dismutase, glutathione S-transferases, and thioredoxin reductase), and DNA repair mechanisms

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(39407841) diagnosis clinical diagnosis involves two components [1] Elevated anion gap, which remains unexplained despite rigorous evaluation

Peroxidation of Polyunsaturated Fatty Acids by Lipoxygenases Drives Ferroptosis