Pathological causes of elevated B12 warrant careful consideration: Haematological disorders : Myeloproliferative neoplasms (polycythaemia vera, chronic myeloid leukaemia), acute leukaemia, and lymphoproliferative disorders can increase B12-binding proteins (transcobalamin and haptocorrin), elevating total serum B12 [3] Liver disease : Hepatocellular damage releases stored B12 into circulation
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4 PubMed (2021)LC-MS/MS assay for 5-amino-1-methylquinolinium: pharmacokinetics and oral bioavailability
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Elevated post-meal insulin directly inhibits the lipolytic pathway that AOD-9604 activates