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Long-term pioglitazone treatment for patients with nonalcoholic steatohepatitis and prediabetes or type 2 diabetes mellitus: a randomized trial

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on the other hand, it can increase paracellular permeability and result in an enhancement of the water content in the colon lumen 26,27

These metabolic benefits often appear before significant weight loss occurs, suggesting mechanisms beyond simple calorie reduction

Clinical management of hypertriglyceridemia in the prevention of cardiovascular disease and pancreatitis

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