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Mutations in IDH can lead to metabolic reprogramming in cancer cells, where -KG is diverted into pathways that promote cell growth and survival

This has brought up the question of why now

While this small case study doesnt provide strong scientific evidence that these drugs can also be used to treat alcohol use disorder, experts say it does reinforce the need for larger, randomized clinical trials that are in early stages

For those researching weight management medications, reading about Wegovy dosing provides helpful context on similar peptide-based treatments

You need comprehensive lifestyle modification: resistance training to preserve muscle, adequate protein intake, nutritional counselling, behavioural support

2018 Nov 13;9(1):4630