Cold fluid entering warm tissue causes vasoconstriction (blood vessel narrowing) at the injection site, which can slow initial absorption and increase the sensation of pressure
Some of it is marketing
The benefits usually outweigh the temporary discomfort
A more complete plateau, when the scale essentially stops moving, typically arrives between 12 and 18 months for most patients, though a small proportion will continue losing weight for up to two years
GORD is a recognised side effect of GLP-1 receptor agonists, occurring because delayed gastric emptying may increase pressure within the stomach and promote reflux of acidic contents into the oesophagus
Digestive Health: Understanding that semaglutide can affect gastric emptying, we assess any existing gastrointestinal conditions, such as gastroparesis or post-surgical changes, to prevent exacerbation