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In Zip7-knockdown THP-1 cells, phagocytosis is notably less efficient, through this deficiency can be reversed by zinc supplementation

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Expect waves of mild nausea, bloating, or slower stomach emptying during dose increases, which then settle if you keep the dose the same, as your body needs time to adjust

Tirzepatide also affects B12 absorption through similar mechanisms: reduced gastric acid and delayed emptying