glp-1 kidney function Role of Agonists & SGLT-2 Inhibitors in Care GLP-1 receptor agonists effects on

This approach improves the delivery of therapeutics into CNS, as well as offers alternative approaches for the treatment of various neurodegenerative conditions

Furthermore, GLP-1 reduces the inactivating phosphorylation of PDH, effectively redirecting glucose metabolism away from anaerobic glycolysis toward more efficient mitochondrial oxidation (Morales et al., 2014

10.1007/s00438-004-0986-8 101 PastoriG

- Maintenance doses (e.g., bi-weekly) follow to sustain benefits

The emergence of GLP-1 agonists and SGLT-2 inhibitors, with their renal protective effects, may offer new avenues for improving outcomes in this patient population

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