if tirzepatide doesn't work will semaglutide didn't Why Am I Not Losing Weight on Tirzepatide? didn't work – Switching Between Semaglutide and Tirzepatide:

Additionally, recent shortages have further complicated access

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24,31 Supply problems, cost and prescribing restrictions in certain countries mean accessing these treatments can be challenging and we have therefore included the recommendation to start metformin if access is a problem

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