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twofold, P = 0.0008)

Cystinosin deficiency leads to impaired lysosomal clearance and disrupted endolysosomal trafficking, which in turn contributes to defective autophagy and altered proteostasis [144, 146, 147]

10.1016/j.cmet.2018.04.012 167 MaE

This highlights the importance of the SNIP1/P-SF3B1 interaction identified here, and the process of spliceosome activation, for proper splicing regulation and the onset of disease

Samples were vacuum-evaporated and dissolved in demineralized water

Before starting any supplementation or injections, consult your doctor to determine the best approach for your individual health needs