GLP-1 then sends a signal to your pancreas that causes the release of insulin, which tells your cells to take in glucose from your blood, lowering your blood sugar
Older anti-obesity medications such as orlistat functioned mainly through local gastrointestinal mechanisms, inhibiting fat absorption and resulting in a weight loss of 23% (Bansal et al
It was that knowledge of glucagon sequence, and its biologywhich actually was very critical for my discovery of GLP-1. Originally thought to be simply responsible for triggering insulin secretion by the pancreas, scientists soon discovered that the hormone also inhibits glucagon secretion by the pancreas and delays gastric emptying
GLP-1RAs have also been effective as an adjunct therapy (for example, in combination with nicotine replacement therapy)
GLP-1 stands for glucagon-like peptide-1, but dont let the fancy name scare you offits just a helper your body already makes
For many people, these medications have produced significant health benefits, including improved blood sugar control and reduced risk factors for chronic disease