doi: 10.1371/journal.pone.0260549 22 ZhengZ.WuK.RuanQ.LiD.LiuW.WangM.et al
Contact your GP or diabetes specialist nurse within 24-48 hours if you notice: Persistent rash or hives lasting more than a few days Injection site reactions that worsen rather than improve, or don't resolve within a week Signs of localised infection: increasing redness, warmth, swelling, or pus at injection sites New skin lesions, particularly if they're painful, bleeding, or changing rapidly Unexplained bruising or skin discolouration Any skin changes accompanied by other symptoms such as joint pain, fever, or general malaise Persistent vomiting or diarrhoea, especially in hot weather, which could lead to dehydration Routine discussion at your next scheduled appointment is appropriate for: Mild, stable injection site reactions that are improving Questions about sun protection or general skin care whilst taking Ozempic Cosmetic concerns related to weight loss Gradual improvement in pre-existing diabetes-related skin conditions Your diabetes care team should conduct regular medication reviews, typically every 3-6 months, which provide an opportunity to discuss any skin-related concerns
Why injection remains preferred despite the learning curve Subcutaneous injection provides the most reliable, consistent drug delivery of any semaglutide formulation
[19] All adverse events including musculoskeletal complaints must be recorded and assessed for potential relatedness to the investigational product by the trial team
no later than February 22, 2025
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