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Critically, this mechanism is selective for senescent cells because non-senescent cells do not accumulate FOXO4 in PML bodies and do not depend on FOXO4-p53 sequestration for survival

At the tissue level, formation of hyaline membranes and alveolar wall oedema and thickening in addition to microvasculature involvement with pulmonary vessel (intra and extra) hyaline thrombosis, hemorrhage, vessel wall oedema, intravascular neutrophil trapping and immune cell infiltration is appreciated [12,13]

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Cell pellets were washed twice with PBS (Fisher Scientific) and stored at -80C prior to further analysis

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J Med Plant Res 5(11):22452251 Lin T-H, Hsieh C-L (2010) Pharmacological effects of Salvia miltiorrhiza (Danshen) on cerebral infarction