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Gebreyohannes EA, Netere AK, Belachew SA

Napoli, J

Study 2 was a 68-week trial that enrolled 1,961 patients with obesity (BMI greater than or equal to 30 kg/m2) or with overweight (BMI 27 to 29.9 kg/m2) and at least one weight-related comorbid condition, such as treated or untreated dyslipidemia or hypertension

IqbalIWilairatanaPSaqibFNasirBWahidMLatifMFet alPlant polyphenols and their potential benefits on cardiovascular health: A review

The drug is sometimes known as a "skinny jab" despite its main purpose being a treatment for type 2 diabetes

The activation is linked to the generation of vasoconstrictive agents, including MCP-1, (pro)renin receptor, endothelin, and angiotensin II, while concomitantly diminishing vasodilatory compounds like nitric oxide, which may contribute to the development of hypertension and lead to decreased viability of cardiomyocytes and myocardial damage