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Soothing effect: While brightening, it strengthens the skin

Some users report skin irritation from the adhesive

Other less common patterns include lipomatous degeneration, with infiltration of dermal nevi by fat cells, and osseous metaplasia

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Thyroid function tests should be monitored periodically (typically every 6-12 months or when symptoms suggest over- or under-replacement), and levothyroxine doses adjusted accordingly