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By investigating the effects of GLP-1 agonists on GSK3-Drp1 signalling, this study uncovered novel mechanisms by which these agents may confer mitochondrial protection and improve RV function in PH

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A., Magalhes C

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animal data only [9] | | HPG axis disruption | Not reported in short-term adult studies | Unknown for pubertal axis | | IGF-1 supraphysiology | Possible at high doses [10] | Elevated baseline