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Description History CJC-1295 without DAC, also referred to as Modified GRF 1-29 or Mod GRF 1-29, is a 30-amino-acid synthetic analog of growth-hormone-releasing hormone (GHRH 1-29) incorporating four amino-acid substitutions D-Ala, Gln, Ala, and Leu that confer resistance to dipeptidyl peptidase-IV cleavage and improve receptor binding stability

They are densely expressed in the hypothalamus, the area postrema, the nucleus tractus solitarius, the nucleus accumbens, the ventral tegmental area, the amygdala, and the hippocampus

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