87 A trial in patients with trichotillomania (hair pulling, see also below under obsessive compulsive disorders) found a clinically significant improvement in depressive symptoms in 44% of patients, compared with 4% in the placebo group, a statistically significant difference
GLP-1R engagement contributes appetite suppression and glucose-dependent insulin secretion
The inclusion of additional services affects the cost of glutathione injections
Safety Considerations and Future Outlook As with all pharmacotherapy for obesity and T2D, establishing cardiovascular safety and demonstrating improvements in meaningful clinical outcomes will be essential, particularly as cardiovascular outcome trials have not yet been completed with multi-agonists (although data are expected soon for tirzepatide: SURPASS-CVOT [T2D] in 2025
No Relief from Over-the-Counter Treatments: If constipation lasts for more than a week despite dietary changes and over-the-counter remedies, or if its severely impacting your quality of life, its time to talk to a doctor
Im collecting questions now for a special mailbag issue of The New Consumer
