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For example, it is postulated that GLP-1R-mediated endocytic carriage across tanycytes or endothelial cells is a specific mechanism by which GLP-1RAs access the brain (55, 113115), although non-receptor-mediated mechanisms such as adsorptive transcytosis are also suggested to be important (116)

However, the possibility of underdosing, contamination, or formulation errors exists in compounded products

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