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NAC is a precursor option with a separate research base and usually costs less per serving

[DOI] [PubMed] [Google Scholar] Ursini F., Maiorino M., Brigelius-Flohe R., Aumann K

Interestingly, mediation analysis showed that TMAOs adverse effect on kidney function strengthened at more severe stages of cardiometabolic disease, implying TMAO synergy with existing pathology (thereby providing 2-hit model)

Severe gastrointestinal disease: Do not use if you have a history of severe gastrointestinal disease

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Average 3-day nutrient intakes were compared to the DRI using 95% confidence intervals (CI)