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People with certain genetic profiles may be more prone to sleep disruption during initial treatment phases

Tuominen H, Tiihonen J et al (2005)

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This is a recurring hazard in neurodegeneration drug development, where surrogate measures are seductive precisely because clinical endpoints are slow, noisy, and expensive to move

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When formulated as a 150 mg sublingual troche, glutathione is designed to be absorbed directly through the oral mucosa, which may provide a rapid and efficient route of administration, bypassing the gastrointestinal tract and first-pass metabolism in the liver