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Previous studies have shown that higher glucose metabolism is associated with higher BOLD signal amplitudes, and that higher degrees of brain functional connectivity are associated with nonlinear increases in metabolism in healthy subjects by comparing PET and rs-fMRI

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Less common but potentially serious concerns can include pancreatitis, gallbladder problems, dehydration-related kidney injury, severe gastrointestinal reactions, and allergic reactions

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Ben-Amitai D, Laron Z: Effect of insulin-like growth factor-1 deficiency or administration on the occurrence of acne