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Healthcare providers must keep a close eye on patients getting high-dose B12 therapy to handle any side effects well
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Kleczkowska (2025)
These three compounds work together to support fat metabolism and liver health: Methionine: An essential amino acid that plays a critical role in fat breakdown, particularly in the liver
NNMT catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM, the universal methyl donor in cells) to nicotinamide (a form of vitamin B3 and a precursor for NAD+ synthesis), producing 1-methylnicotinamide and S-adenosylhomocysteine (SAH)
It is also important for users to set realistic expectations when starting any new supplement
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