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Zeng et al
Those with psoriasis have a markedly increased risk of developing other major inflammatory disorders, particularly: cardiovascular disease diabetes metabolic syndrome stroke Note: This link between psoriasis and systemic health is underscored by a 5-year diminished life expectancy among those with the disease, largely attributable to increased cardiovascular disease risk
Why frequency is individualized Because response depends on individual metabolism, the underlying reason for use, and adherence, the cadence of injections is a clinical decision