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This study is to explore a GSH-responsive AP probe-net, which can be activated by the abundant GSH in ATC cells to generate reactive alkoxyamine, and the formed alkoxyamine can trap AP sites and block the APE1 activity, leading to ATC cell death but less adverse effects towards normal cells
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Without robust evidence, Americans remain vulnerable when purchasing products that have not undergone regulatory oversight.
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During breast cancer, tumor cells recruit resident fibroblasts [57], adipocytes [58], and/or bone marrow-derived mesenchymal stem cells [59], transforming them into cancer-associated fibroblasts (CAFs), which in turn reshape and remodel the tumor microenvironment
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