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We have shown in the lab that targeting this protein leaves the cancer cells exposed and vulnerable to oxidative stress, blocking their ability to invade other tissues

Carnitine reabsorption from primary urine was one of the most affected processes with an approximately 50% reduction in plasma carnitine levels and a parallel systemic decrease in tissue carnitine content

Elevated levels of pro-inflammatory cytokines such as IL-6 and TNF- are usually related to insulin resistance and alteration of insulin sensitivity in diabetic patients, while they can also be used as markers of renal damage in relation to diabetic nephropathy [131,132,133,134]

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The link to IBS is particularly interesting, as both FM and IBS are comorbid nociplastic pain conditions 6 that may share underlying alterations in gut-brain axis function and BA metabolism