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That thyroid caution traces back to an FDA boxed warning

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The GLP-1 agonist, exenatide, increased fasting EF via endothelial nitric oxide (NO) synthase (eNOS) activation, nitric oxide (NO) production in endothelial cells, induced dose-dependent vasorelaxation, and reduced high-glucose or lipid-induced endothelial dysfunction in arterioles ex vivo [64]

Most infections were caused by Rhodococcus equi, a bacterium that lives in the soil and causes pneumonia in young horses