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To our knowledge, this is the first study of its kind to utilize network pharmacology to identify genes which are associated with epilepsy, are potential targets of the ASMs CBZ and VPA, and are also involved with oxidative stress, to identify proteins of which specific oxidative stress pathways are induced due to CBZ and VPA treatment in epilepsy therapy

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doi: 10.1038/s41590-020-0772-8 87 KoersJMarsmanCSteutenJTolSDerksenNILten BrinkeAet al

Lifestyle factors also play a huge role

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