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The SURMOUNT-1 Phase 3 trial demonstrated that tirzepatide 15mg weekly produced 20.9% mean body weight reduction versus 3.1% placebo

Measurement of ROS production To measure intracellular ROS, the 143B cells were plated in 12-well plates at a density of 3 10 5 cells per well

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Hydroxytyrosol protects against oxidative DNA damage: Anti-inflammatory effect Inflammation creates free radicals and depletes antioxidants