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What the Research Shows In the STEP 1 clinical trial, published in Diabetes, Obesity and Metabolism (Wiley), participants receiving semaglutide 2.4 mg once weekly achieved an average weight loss of 17.3% over 68 weeks, compared with 2.0% in the placebo group

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256 The prognosis remains pessimistic due to the insensitivity to current treatments, even after gross total resection and aggressive postoperative chemoradiotherapy

Metabolic syndrome affects multiple organ systems, whilst fatty liver specifically describes excess fat accumulation in the liver