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There was a close relationship between gut microbiota and intestinal mucosal defense barrier and UC incidence in both studies

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R.MamminoK.NoceraJ

Free PUFAs (mainly arachidonic acid, AA) must be esterified to membrane phospholipids (PLs) by acyl-CoA synthase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3(LPCAT3)

The European Food Safety Authority (EFSA) issued a 2018 scientific opinion concluding that GTE doses at or above 800 mg EGCG/day were associated with "liver safety concerns" and that doses above 400 mg EGCG/day in supplements "could not be considered safe" for regular use [6]

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