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Principal component analysis (PCA) indicated that Day 30 iHLOs exhibited a protein expression pattern more closely aligned with human liver tissue than HepaRG and HepG2 cells (Fig

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There are numerous causes for inflammation of this organ as it is very sensitive to stress, metabolic derangements, or inadequate oxygen (due to poor blood flow), trauma, infectious agents, and potentially drugs, (as recognized in human pancreatitis)