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Sammy Saab, MD, MPH, the medical director of the Pfleger Liver Institute at UCLA Health in Los Angeles, who was also not involved in the study, says, This is the first time theres been a statistical difference in improvement of fibrosis in people on a GLP-1 agonist

Step 1: Pharmacological appetite suppression GLP-1 medications mimic a gut hormone that regulates blood sugar and satiety

Tumor angiogenesis often results in a low-pH and hypoxic TME, which eventually limits drug efficacy

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Adverse Effects In the phase 2 TROPION-Lung05 trial, treatment-related adverse effects (TRAEs) of grade 3 or higher were observed in 28.5% of patients, and the most common included stomatitis (9.5%), nausea (2.2%), and decreased appetite (2.2%)