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Unlike many performance or recovery compounds that are completely foreign to the body, BPC-157 is modeled after a naturally occurring fragment of gastric juice, which is partly why it has drawn so much attention in both research and athletic communities

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Published preclinical data in rodents suggests doses equivalent to 200mg+ in humans produce off-target effects on folate metabolism and S-adenosylmethionine (SAMe) pools

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mdpi.com A firstinhuman tolerability trial administering IV BPC-157 to healthy volunteers showed good safety profiles at doses up to 0.5 mg/kg, setting the stage for future clinical pharmacokinetic and safety assessments