A blockage of ascorbate accumulation in response to high light was also observed when glutathione deficiency was induced pharmacologically by buthionine sulfoximine treatment, providing extra evidence that, in high-light conditions, glutathione acts as a substitute for ascorbate reduction (Figure 1)
J Mol Med, 92(5):483495
M.WardJ
ALA can help reduce the visible effects of fine lines and early signs of aging by supporting collagen function and protecting skin cells from damage
Think of it as acclimation, not optimization
10.3390/ijms26062691 [DOI] [PMC free article] [PubMed] [Google Scholar] Beard JR, Officer A, Carvalho IA, Sadana R, Pot AM, Michel JP, Lloyd-Sherlock P, Epping-Jordan JE, Peeters GM, Mahanani WR, Thiyagarajan JA, Chatterij S (2016) The world report on ageing and health: a policy framework for healthy ageing