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The EC 50 , calculated from the concentrationresponse curve generated using samples from n = 7 patients, was 3.88 10 6 M (Figure 5B)

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Conversely, IGF-1 receptors are also widely expressed but exhibit higher densities in the cortex, hippocampus, and thalamus, with moderate expression in the olfactory bulb, hypothalamus, and cerebellum [95]

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