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Prolotherapy injections typically contain a sugar-like substance or dextrose, while PRP injections contain a concentration of the patient's own platelets [1]

PRP therapy has been extensively studied as a minimally invasive alternative to corticosteroid injections and surgical interventions: A landmark RCT found that PRP injections resulted in significant pain relief and functional improvements compared to corticosteroids at 6-month and 1-year follow-ups (PMID: 19797698)

the agency will make the final regulatory decisions