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The presence of ferric IECs has been observed to cause a disturbance in the intestinal barrier, leading to the release of intestinal microorganisms and an overactive immune response within the intestines

During fermentation, butyrate producers cause substrate-level phosphorylation of the dietary substrate to generate energy in the form of ATP, which results in the formation of multiple end-products, including butyrate (Louis and Flint, 2009)

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