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The progression of HMGB1-induced autophagy in cancer biology

Plast Reconstr Surg 141(3):468e-469e, 2018

The Lau et al

The progression of DN can lead to severe consequences, including pain, loss of sensation, and increased risk of foot ulcers and amputations, which collectively strain global healthcare resources ( The clinical manifestations of DN can vary widely, ranging from asymptomatic cases to severe pain and functional impairment

Its a dual-action medication that mimics both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) hormones