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Administration Issues: Some users of sublingual semaglutide reported problems with the medication separating during shipping, making it difficult to extract from the bottle

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For GLP-1 reconstitution in Bacteriostatic Water, the DPP-IV inhibitor requirement for biological matrix applications applies regardless of reconstitution vehicle , Bacteriostatic Water itself does not contain DPP-IV activity, but any subsequent addition to biological matrices requires DPP-IV inhibitor supplementation