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Research Summary 5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme overexpressed in adipose tissue and linked to obesity and metabolic dysfunction

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NNMT Inhibition Mechanism and Optimal Dosing Range 5-Amino-1MQ functions as a small-molecule competitive inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme responsible for methylating nicotinamide