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Kim-Schulze, S

Development of improved formulations or delivery systems could potentially enhance therapeutic efficacy, reduce dosing frequency, or improve patient compliance with treatment protocols

The FDA maintains the warning as a precautionary measure given the seriousness of the animal findings and the relatively limited duration of human exposure data

Insulin-like growth factor-1 promotes G(1)/S cell cycle progression through bidirectional regulation of cyclins and cyclin-dependent kinase inhibitors via the phosphatidylinositol 3-kinase/Akt pathway in developing rat cerebral cortex

PMID: 33822018 Rubino D, et al

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