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It is a hormone that is naturally produced during pregnancy

While KPV has shown promise in preliminary studies, the FDA requires more comprehensive data before allowing its widespread use in compounded medications

Similarly, lepodisiran has shown well-tolerated and dose-dependent reductions in serum Lp(a) concentrations, with a Phase III trial currently recruiting participants and expected to be completed by 2029 (NCT06292013 and NCT04914546)