Despite B12s importance, deficiency affects an estimated 15% of the general population, with rates climbing significantly higher among certain groups
Morning dosing is generally preferred to align with natural metabolic patterns, though this has not been rigorously studied
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It acts as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme expressed in multiple tissues including adipose tissue and the liver that plays a role in cellular energy metabolism and fat storage
According to a recent study, 500mg of Vitamin C per day is a good amount, but that would require you to eat a lot of citrus fruits on a daily basis