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Glaesner W, Vick AM, Millican R, Ellis B, Tschang SH, Tian Y, et al

Common research protocols use cycles of 4 weeks on, 2 weeks off

Most side effects go away quickly and all are treatable

Within this context, several substrate-dependent metabolic processes may function as rate-limiting determinants of physiological resilience during sustained GLP-1RA therapy (Table 1)

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More info here under the Recommendation for Contraindication and Precautions section: Also, anyone can and should report any symptoms to VAERS (Vaccine Adverse Event Reporting System (VAERS) The more information we can provide them the better