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Self-prescribing or obtaining these medications through unregulated sources poses significant safety risks

The following dosage recommendations apply, unless otherwise prescribed: At the beginning of treatment, 1 vial of VITAMIN B12 DEPOT-ROTEXMEDICA (equivalent to 1000 g hydroxocobalamin acetate) is administered twice a week for the first few weeks after diagnosis

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Some patients may require levothyroxine dose reductions as they lose weight, while the relationship is not always linear or predictable

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