The good news is that this is very manageable
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Sensitivity to platinum-based chemotherapy drugs was then compared in A2780 and A2780/GSTP1 cells and significant differences in chemosensitivity observed following treatment with cisplatin (2.28-fold decrease in IC 50, P =0.03, Figure 2B) and carboplatin (4.83-fold decrease in IC 50, P =0.007, Figure 2C), and a less pronounced decrease in sensitivity to paclitaxel (1.58-fold increase in IC 50, P =0.02, Figure 2D)
520 Imvax is conducting a randomized, multicenter, double-blind, placebo-controlled Phase IIb study (NCT04485949) to evaluate IGV-001 in patients with newly diagnosed GBM
This increase is linked to normal changes in fluid levels and eating habits as weight starts to drop
Matt Williams: Yeah, its just going to depend upon each persons level of risk that they want to take as long as they know the risks and are comfortable with the risks, if theyre comfortable with those risks, and if theyre small and they want to use the drugs for diabetes or weight loss, at least theyre making an informed decision
