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Published in JAMA, the Journal of the American Medical Association, the study found that the use of Glucagon-like peptide agonists increases the risk of bowel obstruction and gastroparesis

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If this happens consistently, switch to a 45-degree angle, use a shorter needle, and always pinch the skin when injecting in the thigh

Post-hoc analysis of the SURMOUNT trial data found that tirzepatide relative to placebo was not associated with increased risk of depressive symptoms