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L-carnitine can be synthesized endogenously or taken with the diet, in particularly through meat and dairy products [71], hence its homeostasis reflects the balance between endogenous biosynthesis, absorption from the diet and renal reabsorption [72]

Among the three main SCFAs, propionate makes a significant contribution to gluconeogenesis, while acetate and butyrate act as key regulators of lipid metabolism in mammals [5], highlighting their functional differences

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The FDA does not conduct premarket review for compounded drugs to evaluate their safety, effectiveness, or quality

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